Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356951 | 0.93 | LMNA (0.47) | ALDH1A1LMNAF2TDP1KMT2A | |
| SCHEMBL3111481 | 0.76 | CA1 (0.43) | ALDH1A1LMNAF2TDP1KMT2A | |
| SCHEMBL1177857 | 0.75 | CA2 (0.49) | — | |
| SCHEMBL10708901 | 0.73 | ALDH1A1 (0.64) | ALDH1A1SRD5A2LMNAF2ELANE | |
| SCHEMBL2363364 | 0.71 | CES2 (0.44) | ALDH1A1LMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL2362643 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1LMNAL3MBTL1KMT2ARAB9A | |
| SCHEMBL6937807 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SRD5A2LMNAF2ELANE | |
| SCHEMBL6937804 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SRD5A2LMNAF2ELANE | |
| Benzophenone SCHEMBL9704194 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SRD5A2LMNAF2ELANE | |
| SCHEMBL17747143 | 0.70 | CA12 (0.44) | ALDH1A1LMNAL3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141394-B2 | More stable analog of isopropyl thiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-11-28 | — | — | US | disclosed |
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-11-11 | — | — | US | disclosed |
| WO-2004094445-A1 | A MORE STABLE ANALOG OF ISO-PROPYLTHIOGALACTOSIDE FOR INDUCTION OF PROTEIN EXPRESSION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2004-11-04 | — | — | WO | disclosed |
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | PPIG, B3GAT3, PPIC | ALDH1A1 3670/4885SRD5A2 4110/4885LMNA 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.