Aminobenzoic Acid

Aminobenzoic Acid

SCHEMBL6028845

Nc1ccc(C(=O)[O-])cc1.Nc1ccc(C(=O)[O-])cc1.[Ca+2]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.54
CA1 P00915 16/20 0.54
CA4 P22748 1/20 0.50
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
APEX1 P27695 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PARP10 Q53GL7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminobenzoic Acid SCHEMBL19611844 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL2270342 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL9316920 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL269265 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL9317385 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL11049339 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL3889308 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL587865 0.95 CA2 (0.61) CA2CA1CA4POLBTDP1
Aminobenzoic Acid SCHEMBL10995557 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA
Aminobenzoic Acid SCHEMBL9316925 0.95 CA2 (0.54) CA2CA1CA4MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303597-B1 USE OF P-AMINOBENZOIC ACID FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF PHOTOALLERGIES LABORATOIRES GALLIER (FR) 1993-06-09 EP claimed
EP-0210751-A2 Halogen-containing rubbers and their manufacture MARINE MAGNESIUM COMPANY (US) 1987-02-04 EP claimed
US-4632954-A WITH AMINOCARBOXY COMPOUNDS CALGON CORPORATION (US) 1986-12-30 US claimed
CN-118420646-B Synergistic auxiliary agent special for recycled polyethylene modified asphalt system and synthetic method and application thereof 山西工程科技职业大学 2024-11-29 CN disclosed
CN-118420646-A Synergistic auxiliary agent special for recycled polyethylene modified asphalt system and synthetic method and application thereof 山西工程科技职业大学 2024-08-02 CN disclosed
EP-3802842-B1 METHOD FOR THE PREPARATION OF AMINOBENZOIC ACID OR AN AMINOBENZOIC ACID DERIVATIVE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-13 EP disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
EP-0514451-B1 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS LIFESCIENCE CORP (US) 1997-01-15 EP disclosed
EP-0514451-A1 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS. UNIV TEXAS (US) 1992-11-25 EP disclosed
WO-1991011117-A2 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-08-08 WO disclosed
EP-0303597-A1 Use of p-aminobenzoic acid for the manufacture of a medicament for the treatment of photoallergies. GALLIER LAB (FR) 1989-02-22 EP disclosed
WO-1988006446-A1 NEW PHARMACEUTICAL COMPOSITIONS PROVIDING PHOTOPROTECTION AND PROCESS FOR OBTAINING THEM LABORATOIRES GALLIER (FR) 1988-09-07 WO disclosed
EP-0210751-A2 Halogen-containing rubbers and their manufacture MARINE MAGNESIUM COMPANY (US) 1987-02-04 EP disclosed
US-4632954-A WITH AMINOCARBOXY COMPOUNDS CALGON CORPORATION (US) 1986-12-30 US disclosed
US-4476318-A REACTING ALKALI METAL SALT OF P-AMINOBENZOIC ACID WITH DIHALOGENATED PROPANE IN APROTIC SOLUENT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1984-10-09 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH CA2 1460/4885CA1 299/4885CA4 819/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A CA2 1048/4885CA1 1255/4885CA4 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.