Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191242 | 0.88 | THRA (0.44) | AKR1B1THRATHRBPTGDR2FABP4 | |
| SCHEMBL17260929 | 0.85 | PTGDR2 (0.44) | AKR1B1THRATHRBPTGDR2FABP4 | |
| SCHEMBL18191122 | 0.84 | FFAR1 (0.51) | PTGDR2LMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL21323478 | 0.82 | KDM4E (0.46) | HPGDLMNAHPDKDM4EPDE4D | |
| Formic Acid SCHEMBL17260885 | 0.81 | PTGDR2 (0.41) | THRATHRBPTGDR2FABP4FABP5 | |
| SCHEMBL6034976 | 0.80 | FABP4 (0.66) | AKR1B1THRATHRBFABP4FABP5 | |
| SCHEMBL20094128 | 0.79 | MAPK14 (0.44) | THRBHPGDLMNAHPDKDM4E | |
| SCHEMBL19685379 | 0.76 | SIGMAR1 (0.40) | THRATHRBFABP4HPGDLMNA | |
| SCHEMBL18191098 | 0.76 | AKR1B1 (0.49) | AKR1B1PTGDR2FABP4FABP5KDM4E | |
| SCHEMBL22449519 | 0.76 | LMNA (0.42) | THRATHRBHPGDLMNAHPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580599-B | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-03 | — | — | CN | disclosed |
| EP-3288950-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-23 | — | — | EP | disclosed |
| EP-3288950-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-23 | — | — | EP | disclosed |
| CN-111484509-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-106536486-B | Herbicidal Pyridazinone Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-01 | — | — | CN | disclosed |
| EP-3169668-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-3169668-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20160304509-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| US-20160304509-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| EP-3063147-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | Syngenta Limited (GB) | 2016-09-07 | — | — | EP | disclosed |
| WO-2016102253-A1 | THIAZOLOPYRIDINONES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102253-A1 | THIAZOLOPYRIDINONES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-30 | — | — | WO | disclosed |
| CN-105683189-A | Herbicidal 3-(2-benzyloxyphenyl)-2,4-dihydroxy-1,8-naphthyridine derivatives | 先正达有限公司 | 2016-06-15 | — | — | CN | disclosed |
| WO-2016008816-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | WO | disclosed |
| WO-2016008816-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | WO | disclosed |
| WO-2015062984-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015062984-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2015-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304509-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | CNPY2, CBR3, DRD1 | AKR1B1 222/4885THRA 1493/4885THRB 1999/4885 |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | AKR1B1 221/4885THRA 3249/4885THRB 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.