Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219226 | 0.85 | NLRP3 (0.44) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29853048 | 0.85 | NLRP3 (0.44) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8409148 | 0.81 | HTR1A (0.53) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27484581 | 0.81 | MAOB (0.48) | FFAR1MAOBPLAU | |
| Fluoride SCHEMBL28325117 | 0.80 | MAOB (0.56) | FFAR1MAOBAKR1B1XDH | |
| SCHEMBL8408981 | 0.80 | PTGER4 (0.53) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6036164 | 0.80 | FABP4 (0.52) | PTGER1PTGER4PTGER3PTGER2FABP4 | |
| SCHEMBL15610227 | 0.80 | AKR1B1 (0.58) | PTGER1PTGER4PTGER3PTGER2FABP4 | |
| SCHEMBL10591847 | 0.80 | FABP4 (0.72) | PTGER1PTGER4PTGER3PTGER2FABP4 | |
| SCHEMBL6036276 | 0.78 | CXCL8 (0.51) | PTGER1PTGER4PTGER3PTGER2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | FFAR1 376/4885PTGER1 3821/4885PTGER4 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.