SCHEMBL6036733

SCHEMBL6036733

Clc1ccc[c]c1Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.42
TSHR P16473 2/20 0.42
DPP4 P27487 1/20 0.41
PGR P06401 4/20 0.37
NSD2 O96028 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
TLR9 Q9NR96 1/20 0.35
LMNA P02545 2/20 0.35
NR1H2 P55055 1/20 0.34
BAX Q07812 1/20 0.34
MAOA P21397 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RHEB Q15382 1/20 0.34
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PARP10 Q53GL7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9499646 0.80 HPGD (0.41) TSHRDPP4LMNARHEBALDH1A1
SCHEMBL2533674 0.78 LTA4H (0.41) LTA4HTSHRDPP4PGRNSD2
SCHEMBL983525 0.78 TSHR (0.44) LTA4HTSHRDPP4LMNANR1H2
SCHEMBL11140990 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL4932041 0.76 LTA4H (0.42) LTA4HTSHRLMNANR1H2BAX
SCHEMBL1929863 0.76 LTA4H (0.42) LTA4HTSHRNSD2HSP90AA1HKDC1
SCHEMBL7803639 0.76 LTA4H (0.43) LTA4HTSHRLMNANR1H2BAX
SCHEMBL422932 0.76 MAOA (0.43) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11141243 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL982444 0.76 LTA4H (0.42) LTA4HTSHRLMNANR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4391804-A Imidazole derivatives and fungicidal composition containing the same HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1983-07-05 US claimed
EP-0033088-B1 ANTIMYCOTIC AGENTS BAYER AG (DE) 1983-05-25 EP claimed
EP-0033088-A2 Antimycotic agents BAYER AG (DE) 1981-08-05 EP claimed
EP-1735007-A2 CYCLODEXTRIN INCLUSION COMPLEXES OF PYRIMIDINE-2,4,6-TRIONES F.HOFFMANN-LA ROCHE AG (CH) 2006-12-27 EP disclosed
WO-2005097058-A2 CYCLODEXTRIN INCLUSIONS COMPLEXES OF PYRIMIDINE-2,4,6-TRIONES F. HOFFMANN-LA ROCHE AG (CH) 2005-10-20 WO disclosed
EP-0400344-B1 Pyridine derivatives and their use as fungicides BASF AG (DE) 1993-12-15 EP disclosed
US-5266579-A Controlling phytopathogens BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
US-5112828-A Horticulture, agriculture BASF AKTIENGESELLSCHAFT (DE) 1992-05-12 US disclosed
US-4911750-A Mixture of a 1,2,4-triazole and phosphorus compound BAYER AKTIENGESELLSCHAFT (DE) 1990-03-27 US disclosed
US-4749405-A 1-vinyltriazole compounds and plant growth and fungicidal compositions BAYER AKTIENGESELLSCHAFT (DE) 1988-06-07 US disclosed
US-4743293-A 1-vinyltraiazole compounds and plant growth and fungicidal composition BAYER AKTIENGESELLSCHAFT (DE) 1988-05-10 US disclosed
EP-0015387-A2 1-Vinyltriazole derivatives, process for their preparation and their use as growth regulating agents and fungicides BAYER AG (DE) 1980-09-17 EP disclosed
EP-0007506-A1 Derivatives of alpha-azolyl ketones, processes for their preparation and their use as fungicides BAYER AG (DE) 1980-02-06 EP disclosed
EP-0007505-A2 Alpha-azolyl-beta-hydroxy-ketones, process for their preparation and their use as fungicides BAYER AG (DE) 1980-02-06 EP disclosed
US-4166827-A DENTAL PLAQUE COOPER LABORATORIES, INC. (US) 1979-09-04 US disclosed
US-4163022-A ANTIPLAQUE AGENTS COOPER LABORATORIES, INC. (US) 1979-07-31 US disclosed
US-4115447-A Carbamylguanidine antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-09-19 US disclosed
US-4115448-A Carbamylguanidine antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-09-19 US disclosed
US-4110328-A Bis-carbamylguanidinoazaalkane antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-08-29 US disclosed
US-4022962-A DENTAL PLAQUE INHIBITORS COOPER LABORATORIES, INC. (US) 1977-05-10 US disclosed