SCHEMBL983525

SCHEMBL983525

[c]1cccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
LTA4H P09960 2/20 0.44
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
HRH1 P35367 1/20 0.40
CTNNB1 P35222 1/20 0.40
SLC6A2 P23975 4/20 0.39
SLC6A4 P31645 4/20 0.39
ALDH1A1 P00352 2/20 0.39
RIPK1 Q13546 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR1A P08908 3/20 0.38
SLC6A3 Q01959 3/20 0.38
KDM1A O60341 2/20 0.38
DPP4 P27487 1/20 0.38
TSPO P30536 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6425203 0.86 ALDH1A1 (0.48) TSHRLTA4HKMT2ASLC6A2SLC6A4
SCHEMBL3348234 0.82 NCOA1 (0.47) TSHRGAAKMT2AALDH1A1HPGD
SCHEMBL5903538 0.82 TSHR (0.42) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL1929863 0.78 LTA4H (0.42) TSHRLTA4HKMT2ANR1H2BAX
SCHEMBL11141243 0.78 LTA4H (0.42) TSHRLTA4HKMT2ANR1H2BAX
SCHEMBL7803639 0.78 LTA4H (0.43) TSHRLTA4HLMNAALDH1A1HPGD
SCHEMBL422932 0.78 MAOA (0.43) TSHRLTA4HGAAKMT2AALDH1A1
SCHEMBL4932041 0.78 LTA4H (0.42) TSHRLTA4HLMNASLC6A2SLC6A4
SCHEMBL9685460 0.78 DPP4 (0.44) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL14695561 0.78 LTA4H (0.43) TSHRLTA4HLMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110053770-A1 SUBSTITUTED AMINOTHIAZOLES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2011-03-03 US claimed
US-5374469-A Using thermoplastic polyimide resin showing adhesive properties by press bending by heating, using low-linear expansion polyimide NITTO DENKO CORPORATION (JP) 1994-12-20 US claimed
EP-0533198-A2 Flexible printed substrate NITTO DENKO CORPORATION (JP) 1993-03-24 EP claimed
CN-110515270-B Photosensitive resin composition, pattern forming method, and method for manufacturing optical semiconductor device 信越化学工业株式会社 2024-07-12 CN disclosed
CN-118103774-A Photosensitive resin composition, photosensitive resin coating, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2024-05-28 CN disclosed
CN-117794985-A Polymer containing silicon phenylene skeleton, photosensitive resin composition, pattern forming method, and method for producing optical semiconductor element 信越化学工业株式会社 2024-03-29 CN disclosed
CN-117120927-A Photosensitive resin composition, photosensitive resin coating film, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2023-11-24 CN disclosed
CN-114746809-A Photosensitive resin composition, photosensitive resin coating film, photosensitive dry film, pattern forming method, and light-emitting element 信越化学工业株式会社 2022-07-12 CN disclosed
CN-114127635-A Photosensitive resin composition, photosensitive dry film, laminate, and pattern formation method 信越化学工业株式会社 2022-03-01 CN disclosed
US-11192853-B2 Separation method and method for producing isocyanate ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-12-07 US disclosed
EP-2641896-B1 SEPARATION METHOD ASAHI CHEMICAL IND (JP) 2020-10-14 EP disclosed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO disclosed
US-5374469-A Using thermoplastic polyimide resin showing adhesive properties by press bending by heating, using low-linear expansion polyimide NITTO DENKO CORPORATION (JP) 1994-12-20 US disclosed
EP-0533198-A2 Flexible printed substrate NITTO DENKO CORPORATION (JP) 1993-03-24 EP disclosed
US-4981942-A Polyamide-imide composition based on bisphenoxyphenyl diamines AMOCO CORPORATION (US) 1991-01-01 US disclosed
US-4861855-A Polyamide-imide compositions from bisphenoxyphenyl diamine tricarboxylic anhydride and tetracarboxylic dianhydride AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4814233-A PROTECTIVE FILMS, COVERTIBLE TO POLYIMIDES; TRI-OR TETRA-CARBOXYLIC ACIDS WITH BENZOPHENONE GROUPS AND DIAMINES CIBA-GEIGY CORPORATION (US) 1989-03-21 US disclosed
WO-1988007563-A1 POLYAMIDE-IMIDE COMPOSITIONS AMOCO CORPORATION (US) 1988-10-06 WO disclosed
US-4696890-A POLYIMIDES BY HEATING A PHOTOCROSSLINKED POLYAMIC ESTER CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
EP-0203030-A2 Coated material and its use CIBA-GEIGY AG (CH) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053770-A1 SUBSTITUTED AMINOTHIAZOLES AND THEIR USE AS FUNGICIDES ABAT, ALDH7A1, TH TSHR 3618/4885LTA4H 720/4885LMNA 4758/4885
US-11192853-B2 Separation method and method for producing isocyanate IDH3A, IDH3B, CA9 TSHR 4739/4885LTA4H 1671/4885LMNA 1338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.