Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038092 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTBMP1NR2F2 | |
| SCHEMBL6038082 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTNR2F2RAB9A | |
| SCHEMBL3940302 | 0.77 | KMT2A (0.59) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6038095 | 0.76 | LMNA (0.64) | ALDH1A1LMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL8864748 | 0.76 | BMP1 (0.54) | ALDH1A1LMNABMP1TAS2R14 | |
| SCHEMBL2275943 | 0.74 | KMT2A (0.51) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6038037 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTNR2F2RAB9A | |
| SCHEMBL6038049 | 0.73 | ALDH1A1 (0.49) | NR1H2NR1H3ALDH1A1LMNAKMT2A | |
| SCHEMBL8558353 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTBMP1RAB9A | |
| SCHEMBL8142192 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTRAB9ASMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | NR1H2 544/4885NR1H3 678/4885ALDH1A1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.