Sugi Predict

Sugi Predict / Compounds / SCHEMBL6044205

SCHEMBL6044205

SCHEMBL6044205

OCc1cc(O)cc(Cl)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 5/20 0.46
▸ CYP3A4 P08684 3/20 0.46
▸ HPGD P15428 3/20 0.46
▸ CRHBP P24387 1/20 0.46
▸ CRHR2 Q13324 1/20 0.46
▸ TSHR P16473 3/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ RECQL P46063 2/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ TTR P02766 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ CASP6 P55212 1/20 0.39
▸ ACHE P22303 2/20 0.39
▸ SHBG P04278 1/20 0.38
▸ HSP90AA1 P07900 2/20 0.37
▸ THRB P10828 2/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776750 1.00 HSD17B10 (0.46) HSD17B10CYP3A4HPGDCRHBPCRHR2
SCHEMBL9999531 0.82 ACHE (0.48) HSD17B10HPGDALDH1A1KDM4ECASP6
SCHEMBL1907836 0.81 HSD17B10 (0.59) HSD17B10CYP3A4HPGDTSHRCYP1A2
SCHEMBL29577605 0.81 HSD17B10 (0.59) HSD17B10CYP3A4HPGDTSHRCYP1A2
Methane SCHEMBL3437667 0.79 ACHE (0.46) HSD17B10HPGDALDH1A1KDM4ECASP6
SCHEMBL9812457 0.79 KDM4E (0.57) HSD17B10CYP3A4HPGDTSHRCYP1A2
SCHEMBL11674645 0.79 HSD17B10 (0.44) HSD17B10CYP3A4HPGDCRHBPCRHR2
SCHEMBL28770766 0.79 HSD17B10 (0.44) HSD17B10CYP3A4HPGDCRHBPCRHR2
SCHEMBL4444016 0.77 SHBG (0.44) HSD17B10CYP3A4HPGDTSHRCYP1A2
SCHEMBL70463 0.76 HSD17B10 (0.65) HSD17B10CYP3A4HPGDCRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104176207-B A kind of method suppressing marine micro-organisms to grow 江苏南通申通机械有限公司 2016-09-07 — — CN claimed
US-8257478-B2 Use of marine fungus originated compounds as antifouling agents THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-09-04 — — US claimed
CN-100408643-C Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2008-08-06 — — CN claimed
CN-1800273-A Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2006-07-12 — — CN claimed
US-20060147410-A1 Use of marine fungus originated compounds as antifouling agents HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2006-07-06 — — US claimed
CN-115678786-B Dandelion endophytic fungi and application thereof 扬州大学 2024-02-23 — — CN disclosed
CN-116003316-A Polyhydroxy cyclohexane derivative, and preparation method and application thereof 浙江大学 2023-04-25 — — CN disclosed
CN-112573999-B Preparation method of 3-chlorogentitol 中国海洋大学 2022-09-02 — — CN disclosed
CN-112573999-A Preparation method of 3-chlorogentitol 中国海洋大学 2021-03-30 — — CN disclosed
CN-104176207-B A kind of method suppressing marine micro-organisms to grow 江苏南通申通机械有限公司 2016-09-07 — — CN disclosed
US-8257478-B2 Use of marine fungus originated compounds as antifouling agents THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-09-04 — — US disclosed
US-8257478-B2 Use of marine fungus originated compounds as antifouling agents THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-09-04 — — US disclosed
US-8257478-B2 Use of marine fungus originated compounds as antifouling agents THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-09-04 — — US disclosed
US-8257478-B2 Use of marine fungus originated compounds as antifouling agents THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-09-04 — — US disclosed
CN-100408643-C Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2008-08-06 — — CN disclosed
CN-100408643-C Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2008-08-06 — — CN disclosed
CN-1800273-A Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2006-07-12 — — CN disclosed
CN-1800273-A Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2006-07-12 — — CN disclosed
US-20060147410-A1 Use of marine fungus originated compounds as antifouling agents HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2006-07-06 — — US disclosed
US-20060147410-A1 Use of marine fungus originated compounds as antifouling agents HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2006-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060147410-A1 Use of marine fungus originated compounds as antifouling agents DDT, PGLS, ACMSD HSD17B10 1325/4885CYP3A4 805/4885HPGD 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.