Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.38 |
| ▸ | PGK2 | P07205 | 3/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL603493 | 0.90 | ACP3 (0.39) | PGK1PGK2ACP3MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL193413 | 0.86 | MMP2 (0.37) | PGK1PGK2ACP3MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL193315 | 0.82 | ACP3 (0.36) | PGK1PGK2ACP3MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL604049 | 0.79 | ACP3 (0.40) | ACP3MMP2MMP9MMP12MAPK1 | |
| Hydrochloric Acid SCHEMBL193049 | 0.78 | ACP3 (0.39) | PGK1PGK2ACP3MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL600629 | 0.77 | ACP3 (0.38) | ACP3MMP2MMP9MMP12MAPK1 | |
| Hydrochloric Acid SCHEMBL2259028 | 0.76 | RAB9A (0.38) | LMNAHTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL604112 | 0.76 | PGK1 (0.33) | PGK1PGK2RAB9A | |
| Hydrochloric Acid SCHEMBL602954 | 0.75 | ACP3 (0.36) | ACP3MMP2MMP9MMP12 | |
| Hydrochloric Acid SCHEMBL604524 | 0.75 | ALDH1A1 (0.47) | ACP3LMNAHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8786932-B2 | Advanced electrode structures and electrochromic devices | NTERA, INC. (US) | 2014-07-22 | — | — | US | claimed |
| US-20120038967-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | NTERA LIMITED (IE) | 2012-02-16 | — | — | US | claimed |
| US-8786932-B2 | Advanced electrode structures and electrochromic devices | NTERA, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120038967-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | NTERA LIMITED (IE) | 2012-02-16 | — | — | US | disclosed |