SCHEMBL6046987

SCHEMBL6046987

O=C1C(Br)=C(c2ccccc2)C(=O)N1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 3/20 0.37
▸ NR1H3 Q13133 3/20 0.37
▸ PDE4B Q07343 2/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ KMT2A Q03164 1/20 0.35
▸ MAPT P10636 4/20 0.34
▸ LMNA P02545 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ BACE1 P56817 1/20 0.34
▸ GAA P10253 2/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ RAD51 Q06609 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALOX12 P18054 1/20 0.33
▸ CCR6 P51684 1/20 0.33
▸ CACNA1B Q00975 1/20 0.33
▸ APBA1 Q02410 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331537 0.76 ALDH1A1 (0.39) KMT2AMAPTALDH1A1MAPK1GAA
SCHEMBL8859515 0.73 ALDH1A1 (0.41) PTGS2MAPTLMNAALDH1A1MAPK1
SCHEMBL5161682 0.70 PDE4B (0.48) PDE4BKMT2AMAPTLMNAALDH1A1
SCHEMBL6046983 0.69 PIM1 (0.33) ALDH1A1
SCHEMBL6674116 0.65 PTGS2 (0.55) NR1H2NR1H3PDE4BPTGS2KMT2A
SCHEMBL29385866 0.64 POLB (0.48) KMT2AMAPTLMNAMAPK1HTT
SCHEMBL1771 0.64 POLB (0.48) KMT2AMAPTLMNAMAPK1HTT
SCHEMBL7686013 0.64 KMT2A (0.53) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL794276 0.64 PTGS2 (0.69) NR1H2NR1H3PDE4BPTGS2MAPT
SCHEMBL29248774 0.64 PTGS2 (0.48) NR1H2NR1H3PDE4BPTGS2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118599234-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-09-06 — — CN disclosed
CN-115087702-B Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-05-31 — — CN disclosed
US-20230099634-A1 STYRENE-BASED RESIN COMPOSITION, FLAME RETARDANT STYRENE-BASED RESIN COMPOSITION, MOLDED BODY, AND PATCH ANTENNA PS JAPAN CORPORATION (JP) 2023-03-30 — — US disclosed
CN-115087702-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2022-09-20 — — CN disclosed
US-20060292450-A1 Non-aqueous electrolyte secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2006-12-28 — — US disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 — — EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 — — US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 — — US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 — — EP disclosed
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