Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377405 | 0.92 | SLC40A1 (0.54) | SLC40A1HSD11B1PRKD1SCN9ACYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1380631 | 0.85 | HTR6 (0.45) | SLC40A1HSD11B1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1380515 | 0.82 | RAD52 (0.43) | SLC40A1RAD52UBE2NL3MBTL1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL1381621 | 0.82 | SLC40A1 (0.52) | SLC40A1HSD11B1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1379813 | 0.79 | HTR6 (0.47) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL1380171 | 0.78 | L3MBTL1 (0.43) | RAD52UBE2NL3MBTL1SLC2A1PRKD1 | |
| SCHEMBL7045097 | 0.77 | SLC40A1 (0.49) | SLC40A1PRKD1HTR6HTR1ADRD2 | |
| SCHEMBL3616367 | 0.76 | HTR6 (0.51) | HSD11B1PRKD1CYP3A4HTR6HTR1A | |
| SCHEMBL3623702 | 0.76 | SLC40A1 (0.58) | SLC40A1HSD11B1PRKD1SCN9AHTR6 | |
| SCHEMBL7045566 | 0.74 | PRKD1 (0.49) | PRKD1CYP3A4HTR6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144883-B2 | Bicyclic sulfonamide compounds | BIOVITRUM AB (SE) | 2006-12-05 | — | — | US | disclosed |