Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619544 | 0.92 | PRKD1 (0.44) | HRH4PRKD1HRH1KCNH2FLT3 | |
| Trifluoroacetic Acid SCHEMBL1380515 | 0.80 | RAD52 (0.43) | L3MBTL1RAD52UBE2NPRKD1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL1381621 | 0.80 | SLC40A1 (0.52) | L3MBTL1RAD52UBE2NPRKD1HTR6 | |
| Trifluoroacetic Acid SCHEMBL1380631 | 0.80 | HTR6 (0.45) | L3MBTL1RAD52UBE2NHRH4PRKD1 | |
| SCHEMBL1380902 | 0.79 | GLO1 (0.51) | PRKD1HTR1ADRD2HTR7HTR6 | |
| Trifluoroacetic Acid SCHEMBL1379813 | 0.79 | HTR6 (0.47) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL6047104 | 0.78 | SLC40A1 (0.47) | L3MBTL1RAD52UBE2NHRH4PRKD1 | |
| SCHEMBL7045566 | 0.77 | PRKD1 (0.49) | PRKD1EPHX2HTR1ADRD2HTR7 | |
| SCHEMBL1380174 | 0.76 | RAD52 (0.36) | L3MBTL1RAD52UBE2NPRKD1PIK3CD | |
| SCHEMBL7045097 | 0.75 | SLC40A1 (0.49) | PRKD1HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1412325-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002100822-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2002-12-19 | — | — | WO | claimed |