Sugi Predict

Sugi Predict / Compounds / SCHEMBL605324

SCHEMBL605324

SCHEMBL605324

CN[C@@H](C)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 2/20 0.48
▸ PGR P06401 1/20 0.48
▸ ADRA2A P08913 1/20 0.48
▸ ADRA2B P18089 1/20 0.48
▸ HRH1 P35367 1/20 0.48
▸ KCNH2 Q12809 1/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ HTR1B P28222 2/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ LMNA P02545 4/20 0.47
▸ CES1 P23141 2/20 0.47
▸ CES2 O00748 1/20 0.47
▸ CYP3A4 P08684 3/20 0.45
▸ TSHR P16473 2/20 0.45
▸ ALOX15 P16050 2/20 0.45
▸ CHRM2 P08172 1/20 0.45
▸ ADRA1A P35348 1/20 0.45
▸ RGS12 O14924 1/20 0.45
▸ GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27525531 1.00 HTR2A (0.48) HTR2APGRADRA2AADRA2BHRH1
SCHEMBL497486 1.00 HTR2A (0.48) HTR2APGRADRA2AADRA2BHRH1
SCHEMBL20471676 1.00 HTR2A (0.48) HTR2APGRADRA2AADRA2BHRH1
Hydrochloric Acid SCHEMBL2914568 0.98 HTR2A (0.47) HTR2APGRADRA2AADRA2BHRH1
Benzoic Acid SCHEMBL27521304 0.94 TSHR (0.54) HTR2APGRADRA2AADRA2BHRH1
Methylamine SCHEMBL27794121 0.94 HTR2A (0.44) HTR2APGRADRA2AADRA2BHRH1
Lactic Acid SCHEMBL27546679 0.92 LMNA (0.46) HTR2APGRADRA2AADRA2BHRH1
SCHEMBL2631351 0.85 TSHR (0.50) HTR1BKMT2ACES1CES2TSHR
SCHEMBL28363603 0.83 PGR (0.48) HTR2APGRADRA2AADRA2BHRH1
SCHEMBL28279721 0.83 LMNA (0.52) HTR2APGRADRA2AADRA2BHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294488-A1 ISOTOPOLOGES, SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF TERRAN BIOSCIENCES INC (US) 2024-09-05 — — US claimed
CN-112645829-B Chiral synthesis method of ephedrine key intermediate (S) -2-methylamino-1-phenyl-1-acetone 浙江普洛康裕制药有限公司 2022-10-21 — — CN claimed
CN-113024391-A Preparation of (S) - (-) -alpha-methylaminopropiophenone 北京旋光普利生物医药科技开发有限公司 2021-06-25 — — CN claimed
CN-112645829-A Chiral synthesis method of ephedrine key intermediate (S) -2-methylamino-1-phenyl-1-acetone 浙江普洛康裕制药有限公司 2021-04-13 — — CN claimed
CN-111233682-A Preparation of (S) - (-) - α -methylaminopropiophenone 北京旋光普利生物医药科技开发有限公司 2020-06-05 — — CN claimed
EP-2884962-B1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INT LLC (US) 2019-05-01 — — EP claimed
US-20150216799-A1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC 2015-08-06 — — US claimed
EP-2884962-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS Smartek International LLC (US) 2015-06-24 — — EP claimed
CN-104119240-A Preparation method for (S)-(-)-alpha-methylaminopropiophenone INST PHARM & TOXICOLOGY AMMS 2014-10-29 — — CN claimed
WO-2014028796-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC (US) 2014-02-20 — — WO claimed
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 — — US claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 — — EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 — — WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 — — US claimed
CN-1293039-C Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative SHANGHAI INST OF MEDICINE INDU (CN) 2007-01-03 — — CN claimed
CN-1293038-C Prepn process of (1R, 2S)-(-)-ephedrine or its hydrochloride SHANGHAI INST OF MEDICINE INDU (CN) 2007-01-03 — — CN claimed
CN-1706812-A Prepn process of (1R, 2S)-(-)-ephedrine or its hydrochloride SHANGHAI INST OF MEDICINE INDU (CN) 2005-12-14 — — CN claimed
CN-1583714-A Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative SHANGHAI MEDICAL INDUSTRY ACAD (CN) 2005-02-23 — — CN claimed
US-20260053829-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION DIAMOND THERAPEUTICS INC (CA) 2026-02-26 — — US disclosed
CN-1583714-A Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative SHANGHAI MEDICAL INDUSTRY ACAD (CN) 2005-02-23 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053829-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION HTR1A, HTR5A, HTR3B HTR2A 6/4885PGR 420/4885ADRA2A 61/4885
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 HTR2A 2551/4885PGR 4044/4885ADRA2A 1525/4885
US-20240294488-A1 ISOTOPOLOGES, SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF CYP11B1, PYGB, CYP11B2 HTR2A 129/4885PGR 789/4885ADRA2A 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.