Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27745837 | 0.98 | TRPA1 (0.39) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL30733276 | 0.80 | MAPT (0.48) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL1911943 | 0.80 | MAPT (0.48) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL5436537 | 0.80 | TRPA1 (0.44) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL8280381 | 0.80 | ACHE (0.45) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL16860015 | 0.78 | MAPT (0.46) | TRPA1ATMCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL2861142 | 0.78 | MAPT (0.46) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL585558 | 0.77 | TRPA1 (0.46) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL11181553 | 0.76 | TRPA1 (0.41) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL5164312 | 0.76 | ALDH1A1 (0.37) | TRPA1ATMCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045644-B2 | Imidochromium compounds in catalyst systems for olefin polymerization | BASELL POLYOLEFINE GMBH (DE) | 2006-05-16 | — | — | US | disclosed |
| US-20040214970-A1 | Imidochromium compounds in catalyst systems for olefin polymerization | EQUISTAR CHEMICALS, LP | 2004-10-28 | — | — | US | disclosed |
| US-6784261-B1 | OBTAINED BY A PROCESS ENCOMPASSING THE FOLLOWING PROCESS STEPS: CONTACTING A DIOXOCHROMIUM COMPOUND WITH AN N-SULFINYL COMPOUND, CONTACTING THE REACTION PRODUCT THUS OBTAINED WITH CHLORINE, AT LEAST ONE ACTIVATOR COMPOUND | BASELL POLYOLEFINE GMBH (DE) | 2004-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214970-A1 | Imidochromium compounds in catalyst systems for olefin polymerization | HCCS, PPOX, INF2 | TRPA1 1613/4885ATM 3921/4885CA1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.