SCHEMBL606273

SCHEMBL606273

Cc1ccc(Nc2ccc(-c3ccc(C(C)C)cc3)c(-c3ccccc3)c2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
MAPK1 P28482 4/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 3/20 0.45
ALOX12 P18054 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HTT P42858 2/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 4/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
NPSR1 Q6W5P4 2/20 0.36
TP53 P04637 2/20 0.35
DHODH Q02127 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2150100 0.89 RAPGEF4 (0.46) MAPTSMN1; SMN2MAPK1ALDH1A1LMNA
SCHEMBL606274 0.88 MAPT (0.40) MAPTSMN1; SMN2MAPK1ALDH1A1LMNA
SCHEMBL30477867 0.78 MAPT (0.52) MAPTSMN1; SMN2ALDH1A1LMNAALOX12
SCHEMBL13580077 0.78 MAPT (0.52) MAPTSMN1; SMN2ALDH1A1LMNAALOX12
SCHEMBL10019438 0.78 MAPT (0.52) MAPTSMN1; SMN2ALDH1A1LMNAALOX12
SCHEMBL12388896 0.78 MAPT (0.52) MAPTSMN1; SMN2ALDH1A1LMNAALOX12
SCHEMBL23875735 0.78 MAPT (0.44) MAPTSMN1; SMN2ALDH1A1LMNAALOX12
SCHEMBL3718540 0.75 HPGD (0.59) MAPTSMN1; SMN2MAPK1ALDH1A1LMNA
SCHEMBL1655412 0.74 CNR2 (0.46)
SCHEMBL23868592 0.74 TP53 (0.42) MAPTSMN1; SMN2ALDH1A1LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9577199-B2 Deuterated compounds for electronic applications E I DU PONT NEMOURS AND COMPANY (US) 2017-02-21 US disclosed
US-9260657-B2 Chrysene compounds for luminescent applications E I DU PONT DE NEMOURS AND COMPANY (US) 2016-02-16 US disclosed
EP-2671936-B1 Chrysene compounds for luminescent applications DU PONT (US) 2015-06-24 EP disclosed
EP-2432849-B1 CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS DU PONT (US) 2015-02-25 EP disclosed
US-20150021586-A1 DEUTERATED COMPOUNDS FOR ELECTRONIC APPLICATIONS LG CHEM, LTD. (KR) 2015-01-22 US disclosed
US-8890131-B2 Deuterated compounds for electronic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2014-11-18 US disclosed
US-8759818-B2 Deuterated compounds for electronic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2014-06-24 US disclosed
EP-2674469-A1 Chrysene compounds for luminescent applications E. I. du Pont de Nemours and Company (US) 2013-12-18 EP disclosed
EP-2671936-A1 Chrysene compounds for luminescent applications E. I. du Pont de Nemours and Company (US) 2013-12-11 EP disclosed
EP-2669351-A1 Chrysene compounds for luminescent applications E. I. du Pont de Nemours and Company (US) 2013-12-04 EP disclosed
US-20120037898-A1 CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-16 US disclosed
US-20110215715-A1 CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
EP-2350230-A2 CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS E. I. du Pont de Nemours and Company (US) 2011-08-03 EP disclosed
WO-2011087815-A2 DEUTERATED ZIRCONIUM COMPOUND FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 WO disclosed
US-20110148287-A1 DEUTERATED ZIRCONIUM COMPOUND FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-23 US disclosed
WO-2011071507-A1 DEUTERATED COMPOUND AS PART OF A COMBINATION OF COMPOUNDS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-16 WO disclosed
US-20110133632-A1 DEUTERATED COMPOUND AS PART OF A COMBINATION OF COMPOUNDS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-09 US disclosed
WO-2011028216-A1 DEUTERATED COMPOUNDS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
US-20110037057-A1 DEUTERATED COMPOUNDS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2010059837-A2 CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110215715-A1 CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS CRY2, CRY1, CYBA MAPT 1206/4885SMN1; SMN2 4587/4885MAPK1 2113/4885
US-20120037898-A1 CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS CRY2, CENPE, CRY1 MAPT 1308/4885SMN1; SMN2 4138/4885MAPK1 2874/4885
US-20110148287-A1 DEUTERATED ZIRCONIUM COMPOUND FOR ELECTRONIC APPLICATIONS SLC39A3, SLC39A11, EED MAPT 2542/4885SMN1; SMN2 3669/4885MAPK1 3391/4885
US-20110037057-A1 DEUTERATED COMPOUNDS FOR ELECTRONIC APPLICATIONS DDT, AHR, EED MAPT 3496/4885SMN1; SMN2 3130/4885MAPK1 3329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.