SCHEMBL606331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL282852	0.96	GAA (0.38)	ALDH1A1GAASMN1; SMN2ALOX12L3MBTL3
	SCHEMBL188655	0.91	GAA (0.40)	GAASMN1; SMN2ALOX12L3MBTL3L3MBTL1
	SCHEMBL1815582	0.88	SLC18A3 (0.40)	ALDH1A1GAASMN1; SMN2ALOX12L3MBTL3
	SCHEMBL188362	0.85	ADRA2C (0.42)	ALDH1A1GAAL3MBTL1
	SCHEMBL286304	0.79	SLC18A3 (0.56)	ALDH1A1GAASMN1; SMN2ALOX12SLC18A3
	SCHEMBL283083	0.78	DRD2 (0.47)	ALDH1A1FGFR3
	SCHEMBL27879361	0.77	L3MBTL3 (0.53)	ALDH1A1GAAL3MBTL3L3MBTL1GRIN2B
	SCHEMBL282115	0.77	ALDH1A1 (0.44)	ALDH1A1SMN1; SMN2L3MBTL3L3MBTL1EML4
	SCHEMBL24124031	0.77	GAA (0.50)	ALDH1A1GAASMN1; SMN2ALOX12SLC18A3
	SCHEMBL188544	0.75	SLC18A3 (0.38)	ALDH1A1SMN1; SMN2SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.