Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339469 | 0.84 | METAP2 (0.43) | TDP1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL22739330 | 0.81 | TDP1 (0.45) | TAAR1THRBALDH1A1RECQLMMP8 | |
| SCHEMBL7268813 | 0.81 | CES1 (0.44) | SMN1; SMN2POLBTDP1TSHR | |
| SCHEMBL30800927 | 0.79 | ALDH1A1 (0.39) | TAAR1SMN1; SMN2ALDH1A1RECQLPOLB | |
| SCHEMBL12482713 | 0.77 | MMP8 (0.35) | THRBALDH1A1MMP8POLBNPSR1 | |
| SCHEMBL2008727 | 0.77 | TAAR1 (0.53) | TAAR1SMN1; SMN2THRBALDH1A1RECQL | |
| SCHEMBL1143435 | 0.77 | POLB (0.48) | TAAR1THRBALDH1A1RECQLMMP8 | |
| SCHEMBL614649 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MMP8POLBLMNA | |
| SCHEMBL991355 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MMP8POLBLMNA | |
| SCHEMBL820513 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MMP8POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084281-B2 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-08-01 | — | — | US | disclosed |
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-07-22 | — | — | US | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | TALDO1, HDHD5, TKT | TAAR1 1495/4885SMN1; SMN2 4691/4885THRB 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.