Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLD1 | P28340 | 1/20 | 0.57 |
| ▸ | TK1 | P04183 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphosphate SCHEMBL6066341 | 0.89 | POLB (0.58) | POLBPOLA1POLD1TK1LMNA | |
| Triphosphate SCHEMBL27892350 | 0.88 | POLB (0.61) | POLBPOLA1POLD1TK1 | |
| SCHEMBL18855348 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL77582 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL265387 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL30586988 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL3031874 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| Triphosphate SCHEMBL6138574 | 0.87 | POLB (0.58) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL154177 | 0.86 | POLB (0.65) | POLBPOLA1POLD1TK1ALB | |
| Triphosphate SCHEMBL81707 | 0.85 | POLB (0.55) | POLBPOLA1POLD1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7051061-A | — | — | None | — | — | JP | disclosed |
| US-10428380-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190031706-A1 | MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-01-31 | — | — | US | disclosed |
| US-20180100191-A1 | ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR INHIBITING PYROPHOSPHOROLYSIS | VISIGEN BIOTECHNOLOGIES, INC. | 2018-04-12 | — | — | US | disclosed |
| US-9845500-B2 | Enzymatic nucleic acid synthesis: compositions and methods for inhibiting pyrophosphorolysis | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160244822-A1 | ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR INHIBITING PYROPHOSPHOROLYSIS | Life Technologies Corporation | 2016-08-25 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-9243284-B2 | Enzymatic nucleic acid synthesis: compositions and methods for inhibiting pyrophosphorolysis | Life Technologies Corporation (US) | 2016-01-26 | — | — | US | disclosed |
| EP-0915901-A1 | PROPARGYLETHOXYAMINO NUCLEOTIDES | THE PERKIN-ELMER CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5821356-A | FOR PRIMER EXTENSION | THE PERKIN ELMER CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |
| US-5770716-A | CHAIN TERMINATING AND CHAIN EXTENDING NUCLEOTIDES, PRIMER EXTENSION REACTIONS, DNA SEQUENCING, POLYMERASE CHAIN REACTION | THE PERKIN-ELMER CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1998006732-A1 | PROPARGYLETHOXYAMINO NUCLEOTIDES | THE PERKIN-ELMER CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |
| WO-1997037041-A2 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM, INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| JP-H0751061-A | THERMOSTABLE DNA POLYMERASE AND ITS PRODUCTION | TAKARA SHUZO CO LTD | 1995-02-28 | — | — | JP | disclosed |
| EP-0457824-A4 | DETECTION OF A NUCLEIC ACID SEQUENCE OR A CHANGE THEREIN | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0457824-A1 | DETECTION OF A NUCLEIC ACID SEQUENCE OR A CHANGE THEREIN | GENECO PTY LTD (AU) | 1991-11-27 | — | — | EP | disclosed |
| WO-1990009455-A1 | DETECTION OF A NUCLEIC ACID SEQUENCE OR A CHANGE THEREIN | GENECO PTY LTD (AU) | 1990-08-23 | — | — | WO | disclosed |
| JP-H00751061-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180100191-A1 | ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR INHIBITING PYROPHOSPHOROLYSIS | RNGTT, PPA1, PNP | POLB 16/4885POLA1 41/4885POLD1 86/4885 |
| US-20190031706-A1 | MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA | RNGTT, NSUN2, RNMT | POLB 25/4885POLA1 35/4885POLD1 111/4885 |
| US-10428380-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, POLM | POLB 24/4885POLA1 35/4885POLD1 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.