Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712450 | 0.91 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2A6MAOAAURKA | |
| SCHEMBL23795185 | 0.77 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2A6ALDH1A1LMNA | |
| SCHEMBL6067814 | 0.76 | CYP3A4 (0.42) | HSD17B1HSD17B2CYP2A6MAOAAURKA | |
| SCHEMBL6067804 | 0.74 | ALDH1A1 (0.42) | HSD17B1HSD17B2MAOATSHRALDH1A1 | |
| SCHEMBL9193008 | 0.72 | CYP2A6 (0.50) | HSD17B1HSD17B2CYP2A6TSHRALDH1A1 | |
| SCHEMBL4454574 | 0.71 | APP (0.70) | HSD17B1HSD17B2CYP2A6IKBKB | |
| SCHEMBL30393125 | 0.70 | CYP2A6 (0.48) | HSD17B1HSD17B2CYP2A6TSHRALDH1A1 | |
| SCHEMBL5673936 | 0.69 | HSD17B1 (0.93) | HSD17B1HSD17B2 | |
| SCHEMBL5712508 | 0.69 | ALOX15 (0.41) | HSD17B1HSD17B2CYP2A6MAOATSHR | |
| SCHEMBL5704914 | 0.68 | CA1 (0.44) | HSD17B1HSD17B2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | disclosed |
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | disclosed |
| CN-1633426-A | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2005-06-29 | — | — | CN | disclosed |
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | KRT18, DSP, COL1A1 | HSD17B1 746/4885HSD17B2 1218/4885CYP2A6 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.