Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385232 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6070187 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KMT2AKCNH2 | |
| SCHEMBL1206839 | 0.66 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL3695615 | 0.65 | ALDH1A1 (0.40) | ALDH1A1HTR2AHRH1HTR2CKCNH2 | |
| SCHEMBL11700264 | 0.64 | BRD4 (0.42) | ALDH1A1OPRM1MAPTKCNH2ADRA1A | |
| SCHEMBL29506875 | 0.63 | THRB (0.44) | MEN1KMT2AKIF11CYP2C19HTR1A | |
| SCHEMBL6070424 | 0.63 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL21219221 | 0.63 | THRB (0.44) | MEN1KMT2AKIF11CYP2C19HTR1A | |
| SCHEMBL8711235 | 0.62 | KMT2A (0.37) | OPRM1MEN1KMT2AKIF11HTR1A | |
| SCHEMBL14968487 | 0.62 | L3MBTL1 (0.41) | ALDH1A1OPRM1MEN1KMT2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034055-B1 | 2-aminoindane analogs | PRESCIENT NEUROPHARMA INC. (CA) | 2006-04-25 | — | — | US | disclosed |