Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070187 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KMT2AKCNH2L3MBTL1 | |
| SCHEMBL1206839 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3695615 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NPSR1HTR2AHRH1HTR2C | |
| SCHEMBL9853856 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6070188 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTTACR1 | |
| SCHEMBL6070193 | 0.70 | HTT (0.34) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL9383419 | 0.69 | PGR (0.39) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL11704517 | 0.68 | BRD4 (0.38) | ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL9384409 | 0.68 | CA12 (0.39) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL11704243 | 0.67 | BRD4 (0.37) | ALDH1A1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194400-A1 | 2-AMINOINDANE ANALOGS | Prescient Neuropharma Inc. (CA) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002342-A1 | 2-AMINOINDANE ANALOGS | IGT PHARMA INC. (CA) | 2001-01-11 | — | — | WO | disclosed |