Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385232 | 0.70 | ALDH1A1 (0.50) | HTTMAPTL3MBTL1AKR1B1MEN1 | |
| SCHEMBL9853856 | 0.69 | ALDH1A1 (0.41) | HTTMAPTAKR1B1MEN1KMT2A | |
| SCHEMBL9384409 | 0.68 | CA12 (0.39) | MAPTAKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL9383419 | 0.68 | PGR (0.39) | MAPTAKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL9388117 | 0.67 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1FFAR1TP53 | |
| SCHEMBL9385854 | 0.65 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| Bicarbonate SCHEMBL11083414 | 0.64 | CES2 (0.40) | MAPTEGFRL3MBTL1ADORA3MEN1 | |
| SCHEMBL30972518 | 0.63 | ALDH1A1 (0.49) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15691695 | 0.62 | ALDH1A1 (0.46) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17051237 | 0.62 | ALDH1A1 (0.46) | HTTMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034055-B1 | 2-aminoindane analogs | PRESCIENT NEUROPHARMA INC. (CA) | 2006-04-25 | — | — | US | disclosed |