Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6071622 | 0.81 | ALDH1A1 (0.44) | LMNAKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.77 | SLC18A3 (0.62) | — | |
| Trifluoroacetic Acid SCHEMBL6072183 | 0.76 | GPR6 (0.50) | LMNAKMT2ASMN1; SMN2ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL6072022 | 0.75 | SLC18A3 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL6071748 | 0.75 | PLA2G7 (0.44) | MEN1KMT2AALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL6071881 | 0.74 | LMNA (0.46) | LMNAMEN1KMT2AHTTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6071640 | 0.74 | SLC18A3 (0.64) | SMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6072181 | 0.73 | SLC18A3 (0.56) | LMNAMEN1KMT2AGAACYP2C19 | |
| Trifluoroacetic Acid SCHEMBL6071855 | 0.73 | SLC18A3 (0.45) | LMNAGAAHTTALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.73 | SLC18A3 (0.54) | MEN1KMT2AUSP2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | LMNA 4727/4885MEN1 2336/4885KMT2A 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.