Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6071622 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL6071803 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6645611 | 0.80 | ALDH1A1 (0.56) | GPR6KDM4EALDH1A1L3MBTL1NPSR1 | |
| Trifluoroacetic Acid SCHEMBL6071817 | 0.79 | FAAH (0.43) | KDM4EMAPK1CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL6072022 | 0.78 | SLC18A3 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL6071748 | 0.78 | PLA2G7 (0.44) | KDM4EALDH1A1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL6071881 | 0.78 | LMNA (0.46) | ALDH1A1NPSR1LMNAMAPTMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.76 | SLC18A3 (0.62) | MAPK1 | |
| Trifluoroacetic Acid SCHEMBL6071601 | 0.76 | LMNA (0.48) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6071920 | 0.75 | HSD11B1 (0.53) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | GPR6 111/4885KDM4E 4629/4885ALDH1A1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.