Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.77 |
| ▸ | FOS | P01100 | 1/20 | 0.67 |
| ▸ | JUN | P05412 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 3/20 | 0.64 |
| ▸ | BACE1 | P56817 | 3/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607705 | 1.00 | HSD17B3 (0.77) | HSD17B3FOSJUNGSK3BBACE1 | |
| SCHEMBL608872 | 0.88 | HSD17B3 (0.74) | HSD17B3FOSJUNGSK3BBACE1 | |
| SCHEMBL608873 | 0.88 | HSD17B3 (0.74) | HSD17B3FOSJUNGSK3BBACE1 | |
| SCHEMBL814395 | 0.87 | HSD17B3 (1.00) | HSD17B3TLR9MAPTNPC1RAB9A | |
| SCHEMBL3050207 | 0.87 | HSD17B3 (1.00) | HSD17B3TLR9MAPTNPC1RAB9A | |
| SCHEMBL814396 | 0.87 | HSD17B3 (1.00) | HSD17B3TLR9MAPTNPC1RAB9A | |
| SCHEMBL10061363 | 0.86 | MMP8 (0.74) | HSD17B3FOSJUNGSK3BBACE1 | |
| SCHEMBL11319298 | 0.84 | HSD17B3 (0.86) | HSD17B3TLR9MAPTNPC1RAB9A | |
| SCHEMBL11319313 | 0.84 | HSD17B3 (0.86) | HSD17B3TLR9MAPTNPC1RAB9A | |
| SCHEMBL29045953 | 0.82 | HSD17B3 (0.82) | HSD17B3TLR9MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2022-05-19 | — | — | US | disclosed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | disclosed |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-12-10 | — | — | US | disclosed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | disclosed |
| US-10744124-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-18 | — | — | US | disclosed |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-05-14 | — | — | US | disclosed |
| EP-3275465-B1 | THERAPEUTIC COMPOSITIONS COMPRISING A COMBINATION OF A HARMINE AND ISOVANILLIN COMPONENT | ANKH LIFE SCIENCES LTD (IE) | 2020-05-06 | — | — | EP | disclosed |
| US-10576067-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | ANKH LIFE SCIENCES LIMITED (IE) | 2020-03-03 | — | — | US | disclosed |
| US-20170105976-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | Ions Pharmaceutical S.à r.I. (LU) | 2017-04-20 | — | — | US | disclosed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | disclosed |
| US-20150158841-A1 | Curcumin Analogs | THE GENERAL HOSPITAL CORPORATION (US) | 2015-06-11 | — | — | US | disclosed |
| US-20150158841-A1 | Curcumin Analogs | THE GENERAL HOSPITAL CORPORATION (US) | 2015-06-11 | — | — | US | disclosed |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
| WO-2008048410-A9 | DIAGNOSTIC METHODS AND GENETIC MARKERS FOR ALZHEIMER DISEASE | HUMAN BIOMOLECULAR RES INST (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008048410-A2 | DIAGNOSTIC METHODS AND GENETIC MARKERS FOR ALZHEIMER DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744124-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | HSD17B3 2643/4885FOS 4377/4885JUN 2377/4885 |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | HSD17B3 2608/4885FOS 470/4885JUN 2257/4885 |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | HSD17B3 2143/4885FOS 308/4885JUN 1770/4885 |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | HSD17B3 1151/4885FOS 4099/4885JUN 4432/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | HSD17B3 2143/4885FOS 308/4885JUN 1770/4885 |
| US-20170105976-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | HSD17B3 1658/4885FOS 4516/4885JUN 2579/4885 |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | HSD17B3 2643/4885FOS 4377/4885JUN 2377/4885 |
| US-20150158841-A1 | Curcumin Analogs | APP, BACE1, PSEN1 | HSD17B3 3362/4885FOS 3360/4885JUN 1640/4885 |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | HSD17B3 2643/4885FOS 4377/4885JUN 2377/4885 |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | HSD17B3 2643/4885FOS 4377/4885JUN 2377/4885 |
| US-10576067-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | INMT, HNMT, COMT | HSD17B3 1658/4885FOS 4516/4885JUN 2579/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | HSD17B3 3186/4885FOS 465/4885JUN 2775/4885 |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | HSD17B3 4468/4885FOS 4116/4885JUN 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.