Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077582 | 0.91 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL6078718 | 0.83 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL6079328 | 0.81 | KMT2A (0.56) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6078214 | 0.81 | MEN1 (0.57) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6079248 | 0.79 | MEN1 (0.58) | KMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL6079356 | 0.78 | MEN1 (0.56) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL7969673 | 0.77 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6079332 | 0.77 | KMT2A (0.53) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6078213 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6429403 | 0.75 | LMNA (0.62) | KMT2AMEN1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |