SCHEMBL60874

SCHEMBL60874

O=C(O)c1nc2ccccc2cc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
MAPT P10636 3/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KDM4E B2RXH2 5/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
HPGD P15428 2/20 0.53
GAA P10253 2/20 0.53
STAT3 P40763 1/20 0.53
PIM1 P11309 3/20 0.49
MGAM O43451 2/20 0.49
GLA P06280 2/20 0.46
ACHE P22303 1/20 0.46
IKBKB O14920 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
DYRK1A Q13627 1/20 0.41
PRNP P04156 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL31268421 0.84 ALDH1A1 (0.62) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL3891699 0.84 CNR2 (0.53) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL2975427 0.83 KDM4E (0.56) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL3515481 0.83 IKBKB (0.54) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL6196574 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
Zinc Ion SCHEMBL10395382 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
Lithium Ion SCHEMBL2146458 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL8780487 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL243748 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL5838768 0.81 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4078692-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2026-03-18 EP claimed
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR UNIV JIMEI (CN) 2025-09-04 US claimed
US-20240130221-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LIMITED (IE) 2024-04-18 US claimed
US-11871654-B2 Heteroleptic carbene complexes and the use thereof in organic electronics UDC IRELAND LIMITED (IE) 2024-01-09 US claimed
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US claimed
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2023-01-26 US claimed
EP-4078692-A1 COMPOUNDS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2022-10-26 EP claimed
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LIMITED (IE) 2022-05-12 US claimed
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics UDC IRELAND LIMITED (IE) 2021-11-30 US claimed
WO-2021122868-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-24 WO claimed
EP-1442095-A1 ELECTROLUMINESCENT PLATINUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS E. I. du Pont de Nemours and Company (US) 2004-08-04 EP claimed
EP-1442094-A2 ELECTROLUMINESCENT IRIDIUM COMPOUNDS HAVING RED-ORANGE OR RED EMISSION AND DEVICES MADE WITH SUCH COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-04 EP claimed
US-20040068132-A1 Compounds comprising phosphorus-containing metal complexes LG CHEM, LTD. (KR) 2004-04-08 US claimed
WO-2004016710-A1 COMPOUNDS COMPRISING PHOSPHORUS-CONTAINING METAL COMPLEXES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-26 WO claimed
US-20030108771-A1 Electroluminescent platinum compounds and devices made with such compounds E.I. DU PONT DE NEMOURS AND COMPANY 2003-06-12 US claimed
US-20030096138-A1 Electroluminescent iridium compounds having red-orange or red emission and devices made with such compounds LG CHEM, LTD. (KR) 2003-05-22 US claimed
WO-2003040257-A1 ELECTROLUMINESCENT PLATINUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-05-15 WO claimed
WO-2003040256-A2 ELECTROLUMINESCENT IRIDIUM COMPOUNDS HAVING RED-ORANGE OR RED EMISSION AND DEVICES MADE WITH SUCH COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-05-15 WO claimed
US-5212219-A Degradable plastics EPRON INDUSTRIES LIMITED (GB) 1993-05-18 US claimed
US-4983651-A Degradable plastics EPRON INDUSTRIES LIMITED (GB) 1991-01-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB ALDH1A1 3145/4885MAPT 58/4885SMN1; SMN2 4484/4885
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR XDH, DAO, KMO ALDH1A1 635/4885MAPT 4081/4885SMN1; SMN2 4428/4885
US-20040068132-A1 Compounds comprising phosphorus-containing metal complexes VDAC1, ALPL, CACNA2D4 ALDH1A1 3515/4885MAPT 2890/4885SMN1; SMN2 3922/4885
US-20240130221-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885MAPT 100/4885SMN1; SMN2 4353/4885
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 ALDH1A1 2588/4885MAPT 893/4885SMN1; SMN2 3047/4885
US-11871654-B2 Heteroleptic carbene complexes and the use thereof in organic electronics OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885MAPT 100/4885SMN1; SMN2 4353/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 ALDH1A1 2588/4885MAPT 893/4885SMN1; SMN2 3047/4885
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885MAPT 100/4885SMN1; SMN2 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.