Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764824 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL6196574 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL243748 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL8780492 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| Zinc Ion SCHEMBL10395382 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL8780487 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL5838768 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL8780478 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL60874 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDGAASTAT3 | |
| SCHEMBL2975427 | 0.80 | KDM4E (0.56) | ALDH1A1KDM4EHPGDGAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301110-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2024-01-03 | — | — | EP | disclosed |
| EP-3328841-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-10-11 | — | — | EP | disclosed |
| EP-3368520-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-11245079-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-02-08 | — | — | US | disclosed |
| US-11208401-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-12-28 | — | — | US | disclosed |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-09-14 | — | — | US | disclosed |
| EP-3257093-B1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-10971689-B2 | Triphenylene-based materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-04-06 | — | — | US | disclosed |
| US-10957864-B2 | Materials for organic light-emitting devices | MERCK PATENT GMBH (DE) | 2021-03-23 | — | — | US | disclosed |
| WO-2012048781-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-19 | — | — | WO | disclosed |
| WO-2011160758-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011137951-A1 | ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011134577-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011116865-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |
| US-20110201778-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| WO-2011085781-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-07-21 | — | — | WO | disclosed |
| US-20100176386-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2173757-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009003700-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100176386-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | OCIAD2, OCIAD1, OSTC | ALDH1A1 1304/4885KDM4E 4222/4885HPGD 2202/4885 |
| US-11245079-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | ALDH1A1 489/4885KDM4E 1797/4885HPGD 1541/4885 |
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | ALDH1A1 1315/4885KDM4E 2805/4885HPGD 1028/4885 |
| US-11208401-B2 | Materials for organic electroluminescent devices | DDT, CELF2, BRD3 | ALDH1A1 594/4885KDM4E 2894/4885HPGD 1895/4885 |
| US-10957864-B2 | Materials for organic light-emitting devices | L1CAM, EML4, OR10J3 | ALDH1A1 155/4885KDM4E 3297/4885HPGD 1191/4885 |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | PORCN, COASY, AAAS | ALDH1A1 2105/4885KDM4E 3013/4885HPGD 1343/4885 |
| US-20110201778-A1 | Organic Electroluminescent Devices | L1CAM, PIEZO1, OR10J3 | ALDH1A1 56/4885KDM4E 3359/4885HPGD 2118/4885 |
| US-10971689-B2 | Triphenylene-based materials for organic electroluminescent devices | TERT, PIEZO1, EFNA1 | ALDH1A1 147/4885KDM4E 3934/4885HPGD 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.