Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9150589 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL4375705 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL15068042 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL719719 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2025101 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL4378846 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1653807 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7264813 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL194819 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL22204649 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21450 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120859949-B | Composite nano-particles of targeted mesenchymal stem cells and application thereof in preparation of medicines for promoting vascularization bone regeneration | BEIJING STOMATOLOGICAL HOSPITAL, CAPITAL MEDICAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116726723-B | Preparation method of oil-water separation film with switchable interface wettability and optical driving self-cleaning function | CHINA PETROLEUM & CHEMICAL CORP. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119039596-B | Double-ion battery based on MOF-on-MOF framework anode material and high-concentration double-lithium salt electrolyte | SOUTH CHINA University OF TECHNOLOGY ZHUHAI MODERN INDUSTRIAL INNOVATION INSTITUTE (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121800548-B | Modified manganous-manganic oxide and application thereof in soft magnetism | Hunan Shuangfu New Material Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119951576-B | Hydrodenitrogenation catalyst, and preparation method and application thereof | PETROCHINA COMPANY LIMITED (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116314867-B | High-load cobalt-based monoatomic catalyst applied to oxygen reduction and preparation method thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122076407-A | Soil restoration drought-resistant material and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076397-A | Nitrogen-doped zinc-based adsorbent, preparation method thereof and application thereof in radioactive cesium removal | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076489-A | Iron single-atom composite catalyst with double-layer carbon-nitrogen shell structure and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080589-A | Latent curing epoxy resin-based sound absorption and insulation composite material and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-4851291-A | Temperature adaptable textile fibers and method of preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1989-07-25 | — | — | US | claimed |
| US-4780102-A | TREATING WITH CROSSLINKING AGENT AND REACTIVE DYE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1988-10-25 | — | — | US | claimed |
| US-4743266-A | CROSSLINKING, N-METHYLOL COMPOUND, QUATERNARY AMMONIUM COMPOUND | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1988-05-10 | — | — | US | claimed |
| US-4711640-A | Process for crossdyeing cellulosic fabrics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1987-12-08 | — | — | US | claimed |
| US-4629470-A | PADDING WITH AN AQUEOUS SOLUTION OF AN N-METHYLOL CROSSLINKING AGENT, ACID CATALYST AND A CHOLINE SALT AND CURING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1986-12-16 | — | — | US | claimed |
| US-4615708-A | Method for insitu coloring crosslinked cellulosic materials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1986-10-07 | — | — | US | claimed |
| US-4556560-A | TOPICAL APPLICATION OF KIPASE INHIBITING WATER SOLUBLE SALT | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| US-4020210-A | Encapsulated water paper | XEROX CORPORATION (US) | 1977-04-26 | — | — | US | claimed |
| US-3975152-A | DIMETHYLOL DIHYDROXYETHYLENEUREA, ACID CATALYST, BASIC DYE, HYDROXYETHYL CELLULOSE, CURING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-08-17 | — | — | US | claimed |
| US-3947613-A | Process for reducing agent migration during treatment of knitted cotton fabric | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-03-30 | — | — | US | claimed |