Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4375705 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL15068042 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL719719 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2025101 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL4378846 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1653807 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7264813 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL194819 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL60878 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL22204649 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117431564-A | Preparation and application of two-dimensional ZIF-derived ultrathin carbon nano-sheet-based nickel monoatom | 哈尔滨理工大学 | 2024-01-23 | — | — | CN | claimed |
| CN-115888733-B | CO (carbon monoxide)2Hydrogenation aerogel catalyst and preparation method and application thereof | 新疆理工学院 | 2025-05-23 | — | — | CN | disclosed |
| CN-115719815-B | Carbon-based electrocatalyst and catalyst-supported electrode, and preparation and application thereof | 中国科学院大连化学物理研究所 | 2025-02-18 | — | — | CN | disclosed |
| CN-119186570-A | Low-temperature CO2Hydrogenation methanol preparation catalyst, preparation and application | 上海华谊控股集团有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118717977-B | Preparation and application of nano drug Zn-AIP-RES-ICG with dual responsiveness | 山东第二医科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-118832159-A | Zinc-boron-silicon-aluminum-sodium glass coated copper powder with low-temperature sintering oxidation resistance and preparation method and application thereof | 华东理工大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-118717977-A | Preparation and application of nano drug Zn-AIP-RES-ICG with dual responsiveness | 山东第二医科大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-118491542-A | Preparation method and application of BiOI/ZnO photocatalyst for degrading quinolone antibiotics | 哈尔滨理工大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-114426488-B | Method for preparing methylamine by amination of methanol | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118164867-A | Method for preparing N, N-dimethylformamide by two-stage method of methylamine mixed gas | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-117431564-A | Preparation and application of two-dimensional ZIF-derived ultrathin carbon nano-sheet-based nickel monoatom | 哈尔滨理工大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-115719815-A | Carbon-based electrocatalyst, catalyst-supported electrode, preparation and application thereof | 中国科学院大连化学物理研究所 | 2023-02-28 | — | — | CN | disclosed |
| CN-114426488-A | Method for preparing methylamine by amination of methanol | 中国石油化工股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-113720827-A | Nano-silver modified titanium oxide nanotube array and preparation method and application thereof | 安徽大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-110685004-B | Bionic modification-free super-hydrophobic Cu-Zn-CeO2Method for producing a layer and use thereof | 山东科技大学 | 2020-07-28 | — | — | CN | disclosed |
| CN-110685004-A | Bionic modification-free super-hydrophobic Cu-Zn-CeO2Method for producing a layer and use thereof | 山东科技大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-107424910-A | For forming coating fluid, metal-oxide film, field-effect transistor and its manufacture method of metal-oxide film | 株式会社理光 | 2017-12-01 | — | — | CN | disclosed |
| CN-103339714-A | Coating liquid for forming metal oxide thin film, field effect transistor, and method for manufacturing field effect transistor | RICOH CO LTD | 2013-10-02 | — | — | CN | disclosed |
| US-5380692-A | Pollution control | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0532024-A1 | Catalyst for catalytic reduction of nitrogen oxide | SAKAI CHEMICAL INDUSTRY CO., LTD., (JP) | 1993-03-17 | — | — | EP | disclosed |