Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089484 | 0.87 | DPP4 (0.40) | SLC26A4CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL6090532 | 0.83 | SLC26A4 (0.51) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6088674 | 0.83 | SLC26A4 (0.63) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6090343 | 0.82 | RXRA (0.54) | SLC26A4NR4A2NPC1RAB9AKMT2A | |
| SCHEMBL4450809 | 0.81 | NR4A2 (0.58) | SLC26A4NR4A2PTGER4MEN1KMT2A | |
| SCHEMBL4451992 | 0.80 | SLC26A4 (0.53) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6088483 | 0.79 | SLC26A4 (0.52) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6091862 | 0.79 | SLC26A4 (0.52) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6089332 | 0.79 | NR4A2 (0.67) | SLC26A4NR4A2NPC1RAB9APTGER4 | |
| SCHEMBL6087927 | 0.78 | MRGPRX4 (0.53) | SLC26A4NR4A2NPC1RAB9AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |