Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600286 | 0.95 | CTRB1 (0.51) | CTRB1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL24324138 | 0.95 | CTRB1 (0.51) | CTRB1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26569247 | 0.95 | CTRB1 (0.51) | CTRB1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3611336 | 0.94 | CTRB1 (0.50) | CTRB1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26122643 | 0.88 | CTRB1 (0.51) | CTRB1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6091230 | 0.84 | KYNU (0.59) | CYP3A4CYP2C9TSHRCYP2C19CYP1A2 | |
| SCHEMBL6091228 | 0.84 | KYNU (0.59) | CYP3A4CYP2C9TSHRCYP2C19CYP1A2 | |
| SCHEMBL4829896 | 0.83 | CTRB1 (0.68) | CTRB1CYP1A2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25288547 | 0.83 | CTSK (0.52) | CYP3A4CYP2C9TSHRCYP2C19ALDH1A1 | |
| SCHEMBL25240531 | 0.83 | CTSK (0.52) | CYP3A4CYP2C9TSHRCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | MERCK FROSST CANADA & CO. (CA) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | CTSB, CTSK, CTSS | CTRB1 16/4885CYP3A4 3292/4885CYP2C9 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.