Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882189 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPK1TDP1SMN1; SMN2HDAC1 | |
| SCHEMBL7188310 | 0.78 | TAAR1 (0.47) | CYP3A4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL978161 | 0.78 | TAAR1 (0.47) | ALDH1A1TSHRCYP3A4NPC1RAB9A | |
| SCHEMBL10964509 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL8136098 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL4267757 | 0.75 | NPC1 (0.40) | ALDH1A1CYP3A4MAPTNPC1RAB9A | |
| SCHEMBL29384271 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4MAPTNPC1 | |
| SCHEMBL8732450 | 0.74 | MAOA (0.47) | ALDH1A1TSHRMAPTRAB9AKMT2A | |
| SCHEMBL4405018 | 0.73 | ALDH1A1 (0.70) | ALDH1A1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL22388303 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPK1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199857-A1 | Therapeutic agents | ASTRAZENECA UK LIMITED (GB) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199857-A1 | Therapeutic agents | PNLIP, LIPC, GPR119 | ALDH1A1 1468/4885MAPK1 1590/4885TSHR 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.