Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6092901 | 0.85 | FDPS (0.43) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL5673107 | 0.85 | FDPS (0.45) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL6093133 | 0.83 | ITGB3 (0.38) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL6091366 | 0.71 | FDPS (0.55) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL5673422 | 0.70 | FDPS (0.41) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| Hydrochloric Acid SCHEMBL6092755 | 0.70 | FDPS (0.41) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| Acetic Acid SCHEMBL6093122 | 0.68 | NOS2 (0.41) | FDPSSMN1; SMN2NPC1RAB9ANOS3 | |
| SCHEMBL828256 | 0.67 | FDPS (0.53) | FDPSSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL5673108 | 0.67 | NOS2 (0.43) | FDPSSMN1; SMN2NPC1RAB9ANOS2 | |
| SCHEMBL18642522 | 0.65 | FDPS (0.58) | FDPSSMN1; SMN2NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | NOS1, NOS2, NOS3 | FDPS 878/4885SMN1; SMN2 1200/4885NPC1 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.