Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGAV | P06756 | 3/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6093122 | 0.85 | NOS2 (0.41) | ITGB3ITGAVITGB5ITGB6KARS1 | |
| SCHEMBL5673108 | 0.85 | NOS2 (0.43) | ITGB3ITGAVITGB5ITGB6KARS1 | |
| SCHEMBL6092907 | 0.83 | FDPS (0.41) | NOS2SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL5675021 | 0.73 | RIOK2 (0.42) | ITGB3ITGAVITGB5ITGB6NOS2 | |
| SCHEMBL828151 | 0.68 | KARS1 (0.63) | KARS1NOS2SMN1; SMN2NPC1FDPS | |
| Acetic Acid SCHEMBL6092901 | 0.68 | FDPS (0.43) | NOS2SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL5673107 | 0.67 | FDPS (0.45) | NOS2SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL8277604 | 0.66 | KDM4D (0.60) | ITGB3ITGAVITGB5ITGB6KARS1 | |
| SCHEMBL14125389 | 0.65 | KARS1 (0.63) | KARS1NOS2SMN1; SMN2NPC1NOS3 | |
| SCHEMBL15829852 | 0.65 | NOS2 (0.46) | KARS1NOS2SMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | NOS1, NOS2, NOS3 | ITGB3 2574/4885ITGAV 3523/4885ITGB5 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.