Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091959 | 1.00 | LMNA (0.53) | LMNATSHRTTKFFAR2HDAC1 | |
| SCHEMBL4363672 | 0.91 | FFAR2 (0.55) | LMNAFFAR2MEN1KMT2A | |
| SCHEMBL20707804 | 0.86 | ADORA2A (0.46) | KMT2ARAB9AMAPTKDM4ENPC1 | |
| SCHEMBL6092098 | 0.86 | HSD17B10 (0.46) | TSHRRAB9AMAPTKDM4ENPC1 | |
| SCHEMBL4367695 | 0.81 | METAP1 (0.48) | LMNATSHRTTKFFAR2HDAC1 | |
| SCHEMBL4370870 | 0.81 | METAP1 (0.48) | LMNATSHRTTKFFAR2HDAC1 | |
| SCHEMBL4371134 | 0.81 | METAP1 (0.48) | LMNATSHRTTKFFAR2HDAC1 | |
| SCHEMBL4371236 | 0.81 | ROCK2 (0.47) | LMNARAB9AMAPTKDM4ENPC1 | |
| SCHEMBL6093781 | 0.81 | MAPT (0.53) | MEN1KMT2ARAB9AMAPTKDM4E | |
| SCHEMBL4372123 | 0.79 | ALDH1A1 (0.49) | LMNAMEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | AR, SHBG, BRCA1 | LMNA 2221/4885TSHR 1721/4885TTK 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.