Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426918 | 0.88 | NPC1 (0.50) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL24944597 | 0.84 | THRA (0.49) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL14139007 | 0.84 | PSIP1 (0.58) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4682702 | 0.80 | NPC1 (0.50) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4682707 | 0.78 | CA2 (0.59) | KMT2ANPC1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29296547 | 0.78 | NPC1 (0.49) | KMT2ANPC1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL680611 | 0.77 | PSIP1 (0.70) | KMT2AHTTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4682788 | 0.77 | NPC1 (0.47) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL23877120 | 0.76 | NAPRT (0.53) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8966797 | 0.76 | LMNA (0.47) | KMT2ANPC1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195278-A1 | TRICYCLIC INHIBITORS OF INFLUENZA VIRUS ENDONUCLEASE | WEBB THOMAS R (US) | 2021-09-30 | — | — | WO | disclosed |
| WO-2019025156-A1 | SUBSTITUTED PYRROLIDINONES, SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |
| US-7101892-B2 | Sulfone derivatives as 5-HT7 receptor ligands | MERCK SHARP & DOHME LTD. | 2006-09-05 | — | — | US | disclosed |
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | MERCK SHARP & DOHME LTD. (GB) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | HTR7, HTR2C, HTR1A | KMT2A 2168/4885NPC1 3025/4885LMNA 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.