Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000615 | 1.00 | MMP2 (0.59) | MMP2LMNAMC4RLOXL2DPP4 | |
| SCHEMBL12793689 | 0.92 | MMP2 (0.57) | MMP2LMNAMC4R | |
| SCHEMBL6522414 | 0.89 | MMP2 (0.61) | MMP2LMNAMC4RLOXL2DPP4 | |
| SCHEMBL8829950 | 0.87 | LMNA (0.49) | MMP2LMNALOXL2KMT2A | |
| SCHEMBL8136955 | 0.86 | LMNA (0.48) | MMP2LMNALOXL2KMT2A | |
| SCHEMBL5967317 | 0.84 | MMP2 (0.55) | MMP2LMNAKMT2A | |
| SCHEMBL7064628 | 0.84 | MMP2 (0.55) | MMP2LMNADPP7 | |
| SCHEMBL18830580 | 0.84 | MMP2 (0.65) | MMP2LMNAKMT2A | |
| SCHEMBL5967323 | 0.84 | MMP2 (0.55) | MMP2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6802090 | 0.83 | MMP2 (0.54) | MMP2LMNADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040626-B2 | Nanofibers and morphology shifting micelles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-26 | — | — | US | disclosed |
| US-20120149843-A1 | NANOFIBERS AND MORPHOLOGY SHIFTING MICELLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-14 | — | — | US | disclosed |
| US-6995247-B2 | Ac-HEHA and related compounds, methods of synthesis and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040184991-A1 | Ac-HEHA and related compounds, methods of synthesis and methods of use | THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DPT. OF HEALTH AND HUMAN SERVICES | 2004-09-23 | — | — | US | disclosed |
| US-6696551-B1 | RADIOIMMUNOTHERAPY, DECONTAMINATION AND DETOXIFICATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-02-24 | — | — | US | disclosed |
| WO-2000059896-A1 | 225Ac-HEHA AND RELATED COMPOUNDS, METHODS OF SYNTHESIS AND METHODS OF USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149843-A1 | NANOFIBERS AND MORPHOLOGY SHIFTING MICELLES | MFAP1, LGALS4, TLN1 | MMP2 2404/4885LMNA 62/4885MC4R 3862/4885 |
| US-20040184991-A1 | Ac-HEHA and related compounds, methods of synthesis and methods of use | APEH, DOHH, DDAH1 | MMP2 1784/4885LMNA 2326/4885MC4R 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.