Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136955 | 0.87 | LMNA (0.48) | LMNALOXL2MMP2KMT2ACNR1 | |
| SCHEMBL5000615 | 0.87 | MMP2 (0.59) | LMNALOXL2MMP2KMT2A | |
| SCHEMBL6100385 | 0.87 | MMP2 (0.59) | LMNALOXL2MMP2KMT2A | |
| SCHEMBL6893492 | 0.80 | MMP8 (0.46) | — | |
| SCHEMBL12793689 | 0.80 | MMP2 (0.57) | LMNAMMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9308221 | 0.77 | LOXL2 (0.53) | LMNALOXL2KMT2AALDH1A1MEN1 | |
| SCHEMBL3091161 | 0.76 | TSHR (0.53) | LMNALOXL2KMT2AALDH1A1MEN1 | |
| SCHEMBL6100381 | 0.76 | CA2 (0.46) | LMNALOXL2MMP2KMT2AALDH1A1 | |
| SCHEMBL10437254 | 0.76 | CA2 (0.46) | LMNALOXL2MMP2KMT2AALDH1A1 | |
| SCHEMBL6522414 | 0.75 | MMP2 (0.61) | LMNALOXL2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650134-A | Peptides | NOVARTIS AG (FORMERLY SANDOZ LTD.) (CH) | 1997-07-22 | — | — | US | disclosed |
| EP-0607103-A2 | Somatostatin analogs containing chelating groups and their radiolabeled compositions | SANDOZ LTD. (CH) | 1994-07-20 | — | — | EP | disclosed |