Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997967 | 0.82 | KDM4E (0.41) | MAPTMAPK1KDM4EALDH1A1GAA | |
| SCHEMBL7998415 | 0.79 | KDM4E (0.39) | MAPTMAPK1KDM4EALDH1A1GAA | |
| SCHEMBL7996112 | 0.77 | RAB9A (0.51) | KDM4EALDH1A1GAASMN1; SMN2CSNK1D | |
| SCHEMBL7232438 | 0.75 | GLS (0.43) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6100575 | 0.75 | TP53 (0.30) | TP53 | |
| SCHEMBL7997959 | 0.75 | KDR (0.43) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL6100365 | 0.75 | CACNA1H (0.35) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL7998311 | 0.74 | GLS (0.44) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7230936 | 0.74 | GAA (0.47) | ALDH1A1GAACSNK1D | |
| SCHEMBL7735892 | 0.73 | RAB9A (0.46) | MAPTRXFP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112553-B1 | Pesticidal indazole or benzotriazole derivatives | SYNGENTA LIMITED (GB) | 2006-09-26 | — | — | US | disclosed |
| EP-1171437-B1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LTD (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-1171437-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | Syngenta Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063207-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |