SCHEMBL7735892

SCHEMBL7735892

CC(=O)c1ccc(CC(=O)Nc2snc(C)c2Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.46
KMT2A Q03164 4/20 0.46
NPC1 O15118 4/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
POLB P06746 2/20 0.40
FFAR2 O15552 1/20 0.40
BLM P54132 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
MAPK8 P45983 3/20 0.40
CSNK1D P48730 1/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7232438 0.87 GLS (0.43) RAB9ANPC1ALDH1A1MAPTPOLB
SCHEMBL7998311 0.86 GLS (0.44) RAB9ANPC1ALDH1A1MAPTPOLB
SCHEMBL7233873 0.84 MAPK8 (0.54) RAB9AKMT2AMEN1ALDH1A1MAPT
SCHEMBL7994626 0.82 GLS (0.42) RAB9ANPC1ALDH1A1MAPTPOLB
SCHEMBL8094492 0.80 MAPK8 (0.41) ALDH1A1KDM4EGAAMAPK8MAPK10
SCHEMBL7997967 0.79 KDM4E (0.41) RAB9ANPC1ALDH1A1MAPTKDM4E
SCHEMBL7230936 0.78 GAA (0.47) KMT2AMEN1ALDH1A1GAAMAPK8
SCHEMBL8069562 0.77 MAPK8 (0.47) RAB9AKMT2AMEN1MAPTPOLB
SCHEMBL7998415 0.76 KDM4E (0.39) RAB9ANPC1ALDH1A1MAPTKDM4E
SCHEMBL7996112 0.76 RAB9A (0.51) RAB9ANPC1ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403622-B1 FOR CONTROLLING INSECTS, ARACHNIDS, NEMATODES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-11 US disclosed
EP-1119569-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT Bayer Aktiengesellschaft (DE) 2001-08-01 EP disclosed
WO-2000020415-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed