Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994626 | 0.96 | GLS (0.42) | GLSMAPK8FFAR2POLBKDM4E | |
| SCHEMBL8094492 | 0.93 | MAPK8 (0.41) | GLSMAPK8KDM4EALDH1A1GAA | |
| SCHEMBL7232438 | 0.88 | GLS (0.43) | GLSMAPK8FFAR2POLBKDM4E | |
| SCHEMBL7735892 | 0.86 | RAB9A (0.46) | MAPK8FFAR2POLBKDM4EALDH1A1 | |
| SCHEMBL7233873 | 0.85 | MAPK8 (0.54) | GLSMAPK8KDM4EALDH1A1GAA | |
| SCHEMBL7230936 | 0.84 | GAA (0.47) | MAPK8ALDH1A1GAAL3MBTL1 | |
| SCHEMBL8094494 | 0.83 | MAPK8 (0.44) | GLSMAPK8ALDH1A1RAB9AMAPT | |
| SCHEMBL7997967 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1GAARAB9ANPC1 | |
| SCHEMBL8069562 | 0.78 | MAPK8 (0.47) | GLSMAPK8POLBKDM4ERAB9A | |
| SCHEMBL7998415 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |