SCHEMBL7230936

SCHEMBL7230936

Cc1nsc(NC(=O)Cc2ccc(O)c(N)c2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GFER P55789 1/20 0.47
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPK8 P45983 5/20 0.37
CSNK1D P48730 1/20 0.36
ANO1 Q5XXA6 1/20 0.36
HSD17B2 P37059 1/20 0.36
NLRP3 Q96P20 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3027577 0.86 ALDH1A1 (0.45) GAAALDH1A1GFERCA2CA1
SCHEMBL7998311 0.84 GLS (0.44) GAAALDH1A1L3MBTL1MAPK8
SCHEMBL7232438 0.83 GLS (0.43) GAAALDH1A1L3MBTL1MAPK8NLRP3
SCHEMBL7231664 0.82 KMT2A (0.41) ALDH1A1CA2CA1MEN1KMT2A
SCHEMBL7994626 0.81 GLS (0.42) GAAALDH1A1CA2CA1L3MBTL1
SCHEMBL7997967 0.80 KDM4E (0.41) GAAALDH1A1CSNK1D
SCHEMBL8094492 0.78 MAPK8 (0.41) GAAALDH1A1CA2CA1MAPK8
SCHEMBL7735892 0.78 RAB9A (0.46) GAAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL7996112 0.77 RAB9A (0.51) GAAALDH1A1MAPK8CSNK1D
SCHEMBL7998415 0.77 KDM4E (0.39) GAAALDH1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6544989-B2 Fungicidal, insecticidal, acaricidal, molluscicidal or nematicidal composition SYNGENTA LIMITED (GB) 2003-04-08 US disclosed
EP-1100798-B1 BENZAZOLE, BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES SYNGENTA LTD (GB) 2002-09-18 EP disclosed
WO-2001055145-A1 AZINE DERIVATIVES AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2001055139-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
EP-1100798-A1 BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES Zeneca Limited (GB) 2001-05-23 EP disclosed
WO-2000006566-A1 BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES SYNGENTA LIMITED (GB) 2000-02-10 WO disclosed