Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 1.00 |
| ▸ | BACE1 | P56817 | 7/20 | 1.00 |
| ▸ | F3 | P13726 | 2/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | FOS | P01100 | 2/20 | 0.68 |
| ▸ | JUN | P05412 | 2/20 | 0.68 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610787 | 1.00 | GSK3B (1.00) | GSK3BBACE1F3THRBATM | |
| SCHEMBL18699288 | 0.95 | GSK3B (0.91) | GSK3BBACE1F3THRBATM | |
| SCHEMBL18513427 | 0.94 | GSK3B (0.88) | GSK3BBACE1F3THRBATM | |
| SCHEMBL10061359 | 0.90 | GSK3B (0.81) | GSK3BBACE1F3THRBATM | |
| SCHEMBL18886701 | 0.88 | GSK3B (0.79) | GSK3BBACE1F3THRBATM | |
| SCHEMBL18886702 | 0.88 | GSK3B (0.79) | GSK3BBACE1F3THRBATM | |
| SCHEMBL2744098 | 0.87 | F3 (1.00) | GSK3BBACE1F3THRBATM | |
| SCHEMBL14331811 | 0.87 | F3 (1.00) | GSK3BBACE1F3THRBATM | |
| SCHEMBL2744101 | 0.87 | F3 (1.00) | GSK3BBACE1F3THRBATM | |
| SCHEMBL17263396 | 0.86 | GSK3B (0.74) | GSK3BBACE1F3THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2022-05-19 | — | — | US | disclosed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | disclosed |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-12-10 | — | — | US | disclosed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | disclosed |
| US-10751330-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-25 | — | — | US | disclosed |
| US-10744124-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-18 | — | — | US | disclosed |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-05-14 | — | — | US | disclosed |
| EP-3275465-B1 | THERAPEUTIC COMPOSITIONS COMPRISING A COMBINATION OF A HARMINE AND ISOVANILLIN COMPONENT | ANKH LIFE SCIENCES LTD (IE) | 2020-05-06 | — | — | EP | disclosed |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| US-20100292342-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | Annji Pharmaceutical Co., Ltd. (TW) | 2010-11-18 | — | — | US | disclosed |
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
| WO-2008048410-A9 | DIAGNOSTIC METHODS AND GENETIC MARKERS FOR ALZHEIMER DISEASE | HUMAN BIOMOLECULAR RES INST (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008048410-A2 | DIAGNOSTIC METHODS AND GENETIC MARKERS FOR ALZHEIMER DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | WO | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744124-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | GSK3B 2563/4885BACE1 1295/4885F3 4264/4885 |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | GSK3B 920/4885BACE1 1942/4885F3 616/4885 |
| US-20100292342-A1 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof | AR, CYP17A1, CYP19A1 | GSK3B 834/4885BACE1 1270/4885F3 1597/4885 |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | GSK3B 918/4885BACE1 2083/4885F3 474/4885 |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | GSK3B 2770/4885BACE1 60/4885F3 4765/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | GSK3B 2812/4885BACE1 750/4885F3 4781/4885 |
| US-10751330-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | GSK3B 2563/4885BACE1 1295/4885F3 4264/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | GSK3B 918/4885BACE1 2083/4885F3 474/4885 |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | GSK3B 2563/4885BACE1 1295/4885F3 4264/4885 |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | GSK3B 2563/4885BACE1 1295/4885F3 4264/4885 |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | GSK3B 2563/4885BACE1 1295/4885F3 4264/4885 |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | GSK3B 3394/4885BACE1 435/4885F3 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.