Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290660 | 0.81 | HTR2A (0.47) | NPC1RAB9AHTR2AHTR2CHTR7 | |
| SCHEMBL3678830 | 0.78 | MGLL (0.56) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL19754954 | 0.77 | KMT2A (0.53) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL12491968 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2ATHRATHRBTP53 | |
| SCHEMBL2925097 | 0.75 | MEN1 (0.49) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL11010359 | 0.75 | MGLL (0.58) | NPC1RAB9AKMT2AHTR2AHTR2C | |
| SCHEMBL13084751 | 0.75 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL11010367 | 0.75 | MGLL (0.58) | NPC1RAB9AKMT2AHTR2AHTR2C | |
| SCHEMBL28975172 | 0.74 | HTR2A (0.45) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL3674393 | 0.74 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060173042-A1 | Process for the preparation of fexofenadine | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-03 | — | — | US | claimed |
| EP-1575893-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | Ranbaxy Laboratories Limited (IN) | 2005-09-21 | — | — | EP | claimed |
| WO-2004054955-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | RANBAXY LABORATORIES LIMITED (US) | 2004-07-01 | — | — | WO | claimed |
| US-20060173042-A1 | Process for the preparation of fexofenadine | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-03 | — | — | US | disclosed |
| EP-1575893-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | Ranbaxy Laboratories Limited (IN) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004054955-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | RANBAXY LABORATORIES LIMITED (US) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173042-A1 | Process for the preparation of fexofenadine | CMA1, HRH2, MAOA | NPC1 3232/4885RAB9A 2049/4885MEN1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.