SCHEMBL6113249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8137089	0.77	GAA (0.52)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL5079816	0.75	KMT2A (0.55)	ALDH1A1KDM4EKMT2AMAPTMMP2
	SCHEMBL5872644	0.74	ALDH1A1 (0.38)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL3507953	0.74	PTGS2 (0.41)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL646278	0.72	LCK (0.46)	RAPGEF4ALDH1A1TSHRKMT2ASLC1A3
	SCHEMBL6039208	0.72	TLR9 (0.37)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL6113292	0.72	RAPGEF4 (0.38)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL587103	0.72	ALDH1A1 (0.42)	RAPGEF4ALDH1A1TSHRGAAKDM4E
	SCHEMBL1153998	0.72	GAA (0.62)	RAPGEF4ALDH1A1GAAKDM4EKMT2A
	SCHEMBL2005577	0.72	CA2 (0.56)	ALDH1A1TSHRKDM4ECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.