Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183689 | 1.00 | ALDH1A1 (0.44) | ALDH1A1AOC3GAAL3MBTL1TSHR | |
| SCHEMBL6448011 | 0.84 | ALDH1A1 (0.44) | ALDH1A1AOC3GAAL3MBTL1KMT2A | |
| SCHEMBL6490320 | 0.82 | AOC3 (0.62) | AOC3L3MBTL1TSHRMAPK1CHRM2 | |
| SCHEMBL11175185 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1FGFR1FGFR2 | |
| SCHEMBL9245675 | 0.80 | GAA (0.58) | ALDH1A1AOC3GAAL3MBTL1TSHR | |
| SCHEMBL4450372 | 0.80 | GAA (0.58) | ALDH1A1AOC3GAAL3MBTL1TSHR | |
| SCHEMBL7356128 | 0.79 | AOC3 (0.41) | ALDH1A1AOC3GAAL3MBTL1ADRA2A | |
| SCHEMBL846120 | 0.79 | ALDH1A1 (0.48) | ALDH1A1AOC3L3MBTL1TSHRCYP3A4 | |
| SCHEMBL21526725 | 0.78 | ALDH1A1 (0.46) | ALDH1A1AOC3L3MBTL1TSHRMAPK1 | |
| SCHEMBL2082408 | 0.78 | ADRA2A (0.53) | ALDH1A1AOC3L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168835-B2 | Method for preparing propargylic alcohol catalyzed by 2-morpholinoisobornane-10-thiol | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | GRHPR, ADH1C, ADH5 | ALDH1A1 99/4885AOC3 111/4885GAA 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.