Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | SELE | P16581 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809567 | 0.86 | ALDH1A1 (0.47) | SIRT1L3MBTL1MAPTTDP1POLB | |
| SCHEMBL24718397 | 0.84 | RXRA (0.52) | SIRT1L3MBTL1MAPTTDP1TSHR | |
| SCHEMBL13239474 | 0.84 | HPGD (0.65) | SIRT1L3MBTL1MAPTTDP1HPGD | |
| SCHEMBL29539997 | 0.83 | ALDH1A1 (0.49) | SIRT1L3MBTL1MAPTTDP1HPGD | |
| SCHEMBL181631 | 0.83 | ALDH1A1 (0.49) | SIRT1L3MBTL1MAPTTDP1HPGD | |
| SCHEMBL6630671 | 0.81 | SIRT1 (0.77) | SIRT1L3MBTL1MAPTTDP1CYP2C19 | |
| Urea SCHEMBL28254322 | 0.79 | ICAM1 (0.50) | SIRT1L3MBTL1MAPTHSD17B10POLB | |
| SCHEMBL6129061 | 0.79 | RAB9A (0.49) | SIRT1L3MBTL1MAPTPARP1POLB | |
| SCHEMBL29895720 | 0.78 | CES2 (0.54) | L3MBTL1MAPTTDP1CYP2C19HPGD | |
| SCHEMBL2978952 | 0.77 | HPGD (0.64) | SIRT1L3MBTL1MAPTTDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047237-A1 | METHOD FOR SYNTHESISING DIARYL SULPHIDE COMPOUNDS IN A SOLID PHASE | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-05-26 | — | — | WO | claimed |
| WO-2005047237-A1 | METHOD FOR SYNTHESISING DIARYL SULPHIDE COMPOUNDS IN A SOLID PHASE | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-05-26 | — | — | WO | disclosed |