Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835092 | 0.78 | TRPM8 (0.50) | TRPM8KCNA5ALDH1A1HPGDCA1 | |
| SCHEMBL6129335 | 0.78 | TRPM8 (0.43) | TRPM8KCNA5ALDH1A1HPGDCA1 | |
| Menthyl Benzoate SCHEMBL15498193 | 0.70 | ALDH1A1 (0.69) | TRPM8ALDH1A1HPGDCA1CA2 | |
| Menthyl Benzoate SCHEMBL17407563 | 0.70 | ALDH1A1 (0.69) | TRPM8ALDH1A1HPGDCA1CA2 | |
| Menthyl Benzoate SCHEMBL3885473 | 0.70 | ALDH1A1 (0.69) | TRPM8ALDH1A1HPGDCA1CA2 | |
| Menthyl Benzoate SCHEMBL18708099 | 0.70 | ALDH1A1 (0.69) | TRPM8ALDH1A1HPGDCA1CA2 | |
| Menthol SCHEMBL28946770 | 0.70 | TRPM8 (0.62) | TRPM8KCNA5ALDH1A1HPGDCA1 | |
| Menthyl Benzoate SCHEMBL29093424 | 0.69 | ALDH1A1 (0.67) | TRPM8ALDH1A1HPGDCA1CA2 | |
| SCHEMBL4081078 | 0.69 | TRPM8 (0.85) | TRPM8KCNA5TRPV1 | |
| SCHEMBL4083810 | 0.69 | TRPM8 (0.85) | TRPM8KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793478-A4 | ORAL COMPOSITIONS | PROCTER & GAMBLE (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-0801555-B1 | ORAL COMPOSITIONS CONTAINING DIMETHICONE COPOLYOLS | PROCTER & GAMBLE (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-0863742-B1 | GRANULAR POWDERS CONTAINING SILICONE OIL | PROCTER & GAMBLE (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20030099603-A1 | Polybutene containing denture cleanser compositions | RAJAIAH JAYANTH (US) | 2003-05-29 | — | — | US | disclosed |
| US-6491896-B1 | ANTICARIES PARTICLES OR TABLETS COMPRISING ADDITION POLYMERS, BLEACHES AND EFFERVESCENCE GENERATORS | THE PROCTOR & GAMBLE COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-2002074263-A2 | POLYBUTENE CONTAINING DENTURE CLEANSER COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-26 | — | — | WO | disclosed |
| US-6294154-B1 | PROLONGED, RESIDUAL ANTIMICROBIAL AND/OR FLAVOR IMPACT EFFECT. TOOTHPASTE, POWDER, LIQUID DENTIFRICE, MOUTHWASH, DENTURE CLEANSER, CHEWING GUM OR CANDY | PROCTER AND GAMBLE COMPANY | 2001-09-25 | — | — | US | disclosed |
| US-6153567-A | CLEANING COMPOUNDS; DENTURES | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| US-6129906-A | Silicone containing powders | THE PROCTER & GAMBLE COMPANY (US) | 2000-10-10 | — | — | US | disclosed |
| US-6123950-A | A TRIMETHYLSILANOL END CAPPED POLYSILOXANE COPOLYMER WITH POLYETHER BASED ON FLAVORANTS, PERFUMES, COOLANTS OR ANTIMICROBIAL AGENTS AS LIPOPHILE AND DISPLAY IMPROVED RESIDUALITY, IMPACT/EFFICIENCY ON SURFACES TREATED THEREWITH | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1996019194-A1 | SILICONE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019193-A1 | ORAL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019561-A1 | SILICONE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019192-A1 | ORAL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019119-A1 | SILICONE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019191-A1 | ORAL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019190-A1 | ORAL COMPOSITIONS CONTAINING DIMETHICONE COPOLYOLS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| EP-0707470-A1 | DENTURE CLEANSING TABLET CONTAINING DISCRETE AGGLOMERATED BLEACH PRECURSOR PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1994026246-A1 | DENTURE CLEANSING TABLET CONTAINING DISCRETE AGGLOMERATED BLEACH PRECURSOR PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5055305-A | Dental cleansing tablet with alkali metal persulfate and perborate bleaches; bactericidal, effervescent, rapid | RICHARDSON-VICKS, INC. (US) | 1991-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030099603-A1 | Polybutene containing denture cleanser compositions | TAS2R8, TAS2R40, TAS2R42 | TRPM8 6/4885HSD11B1 3871/4885KCNA5 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.