Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129999 | 0.81 | APEX1 (0.34) | APEX1PER2CRY1CRY2 | |
| SCHEMBL2495979 | 0.72 | MGLL (0.41) | — | |
| SCHEMBL6253134 | 0.69 | PER2 (0.41) | APEX1PER2CRY1CRY2ESR1 | |
| SCHEMBL242395 | 0.66 | TSHR (0.42) | PER2CRY1CRY2ESR1 | |
| SCHEMBL3794136 | 0.66 | PER2 (0.44) | APEX1PER2CRY1CRY2ESR1 | |
| SCHEMBL31718392 | 0.66 | SIGMAR1 (0.37) | — | |
| SCHEMBL28341253 | 0.65 | ALDH1A1 (0.37) | — | |
| SCHEMBL7132181 | 0.65 | ALDH1A1 (0.39) | — | |
| Potassium SCHEMBL5140869 | 0.65 | PER2 (0.43) | APEX1PER2CRY1CRY2ESR1 | |
| SCHEMBL29291124 | 0.64 | GABRA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805322-A4 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GEN ATOMICS (US) | 2008-10-08 | — | — | EP | disclosed |
| US-7374897-B2 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1805322-A1 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GENERAL ATOMICS (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006044633-A1 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GENERAL ATOMICS (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084132-A1 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS | 2006-04-20 | — | — | US | disclosed |